tag:blogger.com,1999:blog-8550919611653842066.post8931981535413575566..comments2023-10-24T19:10:17.771-07:00Comments on The High-fat Hep C Diet: Cholesterol is a nutrient, not a food. Pork and cirrhosis revisited.Unknownnoreply@blogger.comBlogger13125tag:blogger.com,1999:blog-8550919611653842066.post-12682460944417017912017-03-30T16:47:53.193-07:002017-03-30T16:47:53.193-07:003 Researches SHOW Why Coconut Oil Kills Belly Fat....<b><a href="http://coconut-diet.syntaxlinks.com/r/CoconutKillsFat" rel="nofollow">3 Researches SHOW</a></b> Why Coconut Oil Kills Belly Fat.<br /><br />The meaning of this is that you actually burn fat by eating Coconut Fats (in addition to coconut milk, coconut cream and coconut oil).<br /><br />These 3 studies from big medical magazines are sure to turn the conventional nutrition world around!Bloggerhttps://www.blogger.com/profile/07287821785570247118noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-60092400972298359522013-12-05T02:38:47.167-08:002013-12-05T02:38:47.167-08:00DIETARY CHOLESTEROL INTAKE IS ASSOCIATED WITH PROG...DIETARY CHOLESTEROL INTAKE IS ASSOCIATED WITH PROGRESSION OF LIVER DISEASE IN PATIENTS WITH CHRONIC HEPATITIS C ???<br /><br />Personally I think, that this is very flawed study based on questionnaires, overlooking many important confounding factors which may influence clinical and histological progression of liver disease in patients with hepatitis C, including virological factors (genotype), nutritional factors (type of fats, micronutrient and anitoxidant intakes), host factors (e.g. type of lipoproteins, ethnicity). Most importantly, prospective studies supports a role of low serum total and LDL-cholesterol and of oxidative stress as positive independent predictive factors of poor RVR in HCV patients. Coversely, high LDL- cholesterol and total cholesterol and lower triglycerides were were associated with higher rates of SVR. There is also significant amount of experimenatal and epidemiological evidence that omega-6 fatty acids increase progression of liver fibrosis. <br /><br />More informations about hepatitis C and diet you can find on my FBP: https://www.facebook.com/MichalPijakMDIntegrativeHepatologyMichalhttps://www.blogger.com/profile/00429529681747820068noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-42141347031417836432013-07-02T03:14:45.796-07:002013-07-02T03:14:45.796-07:00I am thinking Dr Yu may be right, and what his stu...I am thinking Dr Yu may be right, and what his study indicates is the effect of cholesterol, in NAFLD due to diabetogenic diet plus diabetogenic virus, leading to NASH.<br />Cholesterol in a diabetogenic diet = trouble? I'll write this up soon.Puddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-88774133999512489802013-06-29T15:33:14.711-07:002013-06-29T15:33:14.711-07:00I wrote to Dr Yu with the pork data, he replied to...I wrote to Dr Yu with the pork data, he replied to me. He thinks the data suggests a causative effect of cholesterol in the progression of HCV fibrosis and cirrhosis. This would be consistent with the TGF-beta activation seen in the rat model.<br /><br />Note that all subjects in the HALT-C trial, including controls, were non-responders to, or relapsers after, interferon-alpha treatment. I would expect more autoimmune sensitivities in this group.Puddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-54236791793924177712013-06-29T15:27:22.523-07:002013-06-29T15:27:22.523-07:00I listened to a radio program where an expert talk...I listened to a radio program where an expert talked about making oil from coconuts, it's an industrial process. I mean to look into it more, hut things like deodorizing are important. Very few vitamins in the coconut oil but granted, SCFA and MCTs are valuable nutrients. Just wanted to put in a balance to the paleo idea that this oil is universally great and can be a major part of diet. Grated or pulped coconut flesh, frozen or in sealed packs, would be the more paleo version. I tend to use coconut cream rather than the oil.<br /><br />Yes, curing bacon seems to make it less porky. The worst offender may be the pork liverwurst type of sausage.Puddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-81672638279972470762013-06-29T14:44:10.891-07:002013-06-29T14:44:10.891-07:00"pork may be even more strongly associated wi..."pork may be even more strongly associated with alcoholic cirrhosis than alcohol"<br /><br />For some reason my brain repeatedly fails to associate this with bacon, focusing only on pork tenderloins and the like :/<br /><br />On another note, what's up with the coconut oil hate? I usually reserve phrases like "processed empty calorie food" for far more nefarious food-like products. Billhttps://www.blogger.com/profile/05022558754270362782noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-89347617784958993542013-06-29T13:43:55.126-07:002013-06-29T13:43:55.126-07:00Woo, persistent asymptomatic yersinia e. infection...Woo, persistent asymptomatic yersinia e. infection seems to be fairly common. If some people are more sensitive to its presence this may be due to the Black Death, Y. pestis, selecting for immmune sensitivity to generic yersinia proteins. Or not.<br /><br />Effect of pathogens in meat should be more noticable from ground meat than whole.<br /><br />I do think that lipid panels being diet-appropriate is a sign of liver function. In the case of HBV and HCV these depress hepatic cholesterol output for reasons connected with their life cycles.<br /><br />In alcohol/PUFA fed rats, dietary cholesterol 1% protects against hepatic necrosis and immediate toxicity but increases fibrosis. It downregulates COX2 and LDL-R, good, but upregulates TGF-beta, bad.<br /><br />In rats given intragastric ethanol and either corn or fish oil,<br />addition of cholesterol (1%) does not change the degree of<br />fatty infiltration but prevents hepatic necrosis and inflammation and enhances hepatic fibrosis. Cholesterol in this model<br />decreases the enhanced low-density lipoprotein receptor<br />message, eliminates messages for TNF-a and COX-2, and<br />decreases plasma and liver levels of thromboxane B2, and<br />products of lipid peroxidation, whereas it increases transforming growth factor-b message. The anti-inflammatory effects of<br />cholesterol are most likely related to a decreased uptake of<br />arachidonic acid caused by downregulation of the low density lipoprotein receptor and its decreased conversion to<br />eicosanoids via decreased COX-2 activity. Enhanced fibrosis<br />may be mediated by increased transforming growth factor-bPuddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-43081328095381898942013-06-29T05:18:06.326-07:002013-06-29T05:18:06.326-07:00I imagine anything that can promote arthritis and ...I imagine anything that can promote arthritis and inflammation would exacerbate progression of fibrosis of liver, yes. Interesting :D<br /><br />I wonder if cholesterol isn't protective but more of a marker of a healthy functional liver? Liver cooks up cholesterol after all. The sat fat vs PUFA effect is probably def. real though. <br /><br />Maybe moodiness I experience from some kinds of meat isn't necessarily related to amino acid sensitivity (glutamate) but it very well may relate to sensitivity to microbes. This easily explains the observation of poorly handled/old meat tending to be promoting of dysphoria. Kosher meat , or very fresh meat, or eggs, does not. <br /><br />Inositol is implicated in fatty liver and inositol supplements are noted to resolve .<br /><br /><br />I have never observed much significant trouble with pork, although these days I eat pork fairly uncommonly except in form of processed/cured pork fat like pork chicarones or bacon or pepperoni.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-47721300603506309112013-06-28T18:03:36.034-07:002013-06-28T18:03:36.034-07:00Allergy to pork: http://onlinelibrary.wiley.com/do...Allergy to pork: http://onlinelibrary.wiley.com/doi/10.1034/j.1398-9995.2002.23832_5.x/full<br /><br />Our results revealed that cooked and roasted pork meat retained allergenic epitopes capable of inducing IgE-mediated food allergy.<br /><br />Bill, there seems to be a vicious cycle in NASH;<br />oxidised cholesterol stimulates fatty acid synthesis, the fatty acid accumulation (I suspect) increases cholesterol synthesis, and there is an increased rate of DNL from carbohydrate. The liver is the insulin clearing organ so we get hyperinsulinaemia. Also, clearing insulin may be a source of cysteine for hepatic glutathione. This is part of a pet theory, that hyperinsulinaemia and immune complexes can deprive cells - esp. hepatocytes and beta cells - of cysteine, depleting hepatic glutathione and eventually lowering insulin synthesis (which depends on both structural cysteine and reduced glutathione).<br />It has the advantage of being a very simple mechanical theory, the disadvantage that there's no supporting evidence beyond a certain superficial plausibility, and the fact that NAC relieves both pancreatitis and hepatitis.<br />http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091141/Puddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-29811653985111417062013-06-28T16:53:34.671-07:002013-06-28T16:53:34.671-07:00Hepatic cholesterol crystals and crown-like struct...Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis.<br />http://www.ncbi.nlm.nih.gov/pubmed/23417738<br /><br />I have tons of histology slides from broken mouse livers - found loads of Crown-Like Structures but never thought to look for cholesterol crystals...<br /><br />On another note, ACAT inhibitors really were a bad idea.Billhttps://www.blogger.com/profile/05022558754270362782noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-60345693051768104002013-06-28T06:11:49.816-07:002013-06-28T06:11:49.816-07:00I had 3 fried eggs, instead.I had 3 fried eggs, instead.Nigel Kinbrumhttps://www.blogger.com/profile/03368973941328529619noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-21248579399343373832013-06-28T02:18:14.169-07:002013-06-28T02:18:14.169-07:00It is worth noting that, for all the alcohol and p...It is worth noting that, for all the alcohol and pork consumed, the incidence of chronic hepatitis and gluten sensitivity, and the existence of hepatotoxic drugs, radiation and pollutants, cirrhosis is still a rare condition, 0.15% incidence in the USA, and mortality from hepatocellular cancer much rarer, at 3.2 per 100,000 in 2006.Puddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.comtag:blogger.com,1999:blog-8550919611653842066.post-50547013423693062752013-06-27T23:44:04.523-07:002013-06-27T23:44:04.523-07:00I've just had an urge to make pork belly strip...I've just had an urge to make pork belly strips w/sweet chilli sauce, covered in Tesco stir-fry veg mix and microwaved 'till tender. That cooks at <100°C.<br /><br />It's 7:45am here :-/Nigel Kinbrumhttps://www.blogger.com/profile/03368973941328529619noreply@blogger.com