On the other hand it compiles much valuable information that does not appear elsewhere.
A reference first to set the scene:
Reversal of hepatic fibrosis -- fact or fantasy?
Realistic expectations for successful anti-fibrotic therapies reflect solid evidence of fibrosis
regression in patients treated effectively for viral liver disease, as well as growing clarity in
the understanding of mechanisms of extracellular matrix production and degradation.
The paradigms of stellate cell activation and apoptosis remain valuable frameworks for
understanding pathways of hepatic fibrogenesis and fibrosis regression, respectively.
The non-scientific literature on Hep C is full of warnings against supplementing nicotinamide, retinol, and vitamin D3.
These warnings, based on the effects of extreme overdose, have no relevance to normal diet or supplementation at clinical dosages. Restricting these vitamins in the belief that they are dangerous is infinitely more risky than supplementing them. Retinol status, for example, is inversely associated with hepatocellular cancer in prospective studies of populations with chronic viral hepatitis.