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Every day on NZ twitter people are debating what they would do were they the Government about vaccine roll-outs, MIQ, lockdowns, DJ's, and any other thing they can think of that they have absolutely no influence over.
Maybe, like me, you're double-chipped, using the app, wearing the mask, and annoying AF. Maybe you're even boostered up the wazoo. Well done. But y'know what? You're probably going to catch covid. Even if you don't, someone you care about is going to, even if you no longer care about the unvaccinated except as targets of your spite.
And yet, what no-one is talking about, or better yet arguing about in order to straighten out, is what they're doing now to reduce their risk of taking up hospital space when that happens, and what they're going to do to make themselves feel better once they get sick.
The good news is that the symptoms of Omicron are basically flu symptoms - scratchy throat, muscle ache, fatigue, night sweats, no loss of smell of taste. These, apart from the cough, were basically the second shot vax effects for many people. And even for those hospitalised, the average stay is 4 days vs 8 days with Delta. But why go to hospital at all if you can help it? Some people - morons, mostly - posit a false dichotomy between government policy and personal responsibility. But in every area, these are on completely different planes and complement each other. You taking responsibility for your health eases the pressure on a government trying to help those unfortunates who can't or won't.
So without further ado, as they say in places where there is an oversupply of further ado, here are the things I do.
Firstly, I exercise regularly and keep the sugar, seed oil, and refined starch real low; another way of saying this is that I eat whole food (of the cheapest sort, e.g. eggs, mince, the fruit and vege in season), play frisbee or swim every day, and walk the dog. I get as much sun as I can handle, and will take vitamin D in winter, or after a while during the prolonged cloudy weather typical of much of NZ.
Secondly, I eat a little sauerkraut or yoghurt with my meals, or take a cheap probiotic.
Thirdly, I take some supplements - Clinicians Selenium drops (Sodium Selenite), around 150 mcgs (three drops) a day, and x4 if I think I'm coming down with an RNA virus. This works out at around $17 a year. The cheapest Zinc tabs from chemist warehouse, one a day, but mostly when exposure is likely. The cheapest chelated magnesium in the supermarket, 150 mg, most days (but I was taking this already).
If I get sick or obviously exposed, I'll increase the selenium drops to 300mcg 2x daily and take Sanderson's ViraMax, a mixture of elderberry (great, works for flu), echinacea, (great, works for cold), olive leaf extract (olive leaf extract has never worked for me, ever), and andrographis (works very well for all viral respiratory infections, but has a rare side-effect risk of liver damage, probably in people with compromised antioxidant defenses). When I had the RSV last year this combo eliminated symptoms so quickly I wondered if I'd just imagined coughing, sneezing and snotting all over the place on the first day.
Maybe you have different ideas? Please discuss them here or in a public forum.
More:
https://www.newsroom.co.nz/readingroom/book-of-the-week-will-salad-cure-covid
Hepatitis C viraemia is carbohydrate-dependent because the virus piggy-backs on triglyceride assembly and VLDL exocytosis. This makes a very low carbohydrate diet an effective way to control HCV viraemia, HCV-associated autoimmune syndromes, and steatosis. HCV cell entry is via LDL-receptor complex, therefore diets intended to lower LDL via upregulation of the LDL-receptor by restricting saturated fat and increasing polyunsaturated fat will increase hepatocellular infection.
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Thursday, 6 January 2022
Yes, but, what will you do when the Covid comes?
Wednesday, 1 December 2021
My review of selenium, probiotics and vitamin D for COVID-19, meat for mental health, and LCHF for diabetes reversal in MSM
Every so often I am asked to review new or best-selling books related to diet for Newsroom and am encouraged by the Reading Room editor Steve Braunias, a very fine writer indeed, not to hold back.
Here's my "review" of two books on vegetables, which is mostly on the role of selenium, probiotics, and vitamin D in the Covid pandemic, as well as the value of meat in the preservation of mental health, and the promise of LCHF, keto and fasting diets for type 2 diabetes remission.
The more clicks and readers it gets, the more chance I'll have of presenting these types of ideas in mainstream media forums in future.
https://www.newsroom.co.nz/readingroom/book-of-the-week-will-salad-cure-covid
Monday, 22 November 2021
The Mother of all Conspiracies; Oswald and JFK in the 21st Century.
Imagine a counterfactual
America, an alternative history wherein it has always been a well-known and
accepted fact that Lee Harvey Oswald, a lone-wolf Marxist, had assassinated the
President of the United States for rational Marxist reasons as well as
subterranean personal ones. In this America, a school shooting by a paranoid
vegan only encourages logical and evidence-based discussion of gun control and
mental illness, a terror attack by Islamist hijackers is unanimously attributed
to its obvious perpetrators, the Moon is American, and one cannot simply say
that one has won an election which one has lost. It is an America in which Dr
Fauci can sleep easy, and in which, sometimes, a virus is only a virus.
There were conspiracy theorists before JFK of course, indeed Oswald had tried
to kill one of them, General Edwin Walker, the only human target he missed
putting one or more bullets into. Yet the creative JFK theories have had a
wider appeal across American society than the paranoic blend of European
antisemitism and John Birch anti-communism indulged in by Walker and his
contemporaries. Robert Kennedy, as Attorney General, tried to have Walker
committed after he incited the Mississippi University race riots in 1962, but
libertarian psychiatrist Thomas Szasz, opposed to the coercive psychiatry that
was, to be fair, something of a public menace at the time, talked him out of
it. Most people knew Walker was nuts. But with JFK theory you can stay
respectable enough, it’s a hobby that seems to hurt no-one. You can put your
own choice of villain in the frame – the CIA, the FBI, the Mafia, LBJ, the
military-industrial complex, and of course the Cubans or the KGB, though it’s
strange that the Manchurian Candidate option presented in film before the
assassination – because it seemed believable at the time – hasn’t survived in
the modern myth, which is comprised of scenarios entirely discordant with
Oswald’s personal beliefs.
We know what Oswald’s political beliefs were because he wrote them down, and
expressed them relatively freely to those around him, and we know how he wanted
to express those beliefs because we have a reliable witness to his development
as an assassin, Marina Oswald, née Prusakova, whom he married in Minsk during
his defection to the USSR. A year after Lee’s death, Marina spent several
months with Priscilla MacMillan, author of Khrushchev and the Arts; the
Politics of Soviet Culture 1962-1964. (MacMillan, a friend of
Kennedy’s, had also interviewed Lee Oswald during his defection to the USSR, at
which time he told her “I want to give the people of the United States
something to think about” - she was the only person to know both the assassin
and his victim). The book that resulted, Marina and Lee, did not appear
till 1977.
Marina Prusakova, who was not told her father’s identity but came to assume he had
died in a purge, and who was rejected by her mother and step-father, was raised
for a time by her devout grandmother in an Old Regime style. She had sensibly
decided, from her observations of Soviet life growing up, that politics was a
sickness and that anyone interested in politics was sick, but she made a
fateful exception for the young American who was interested in her. Marina may
not have been “political” but she knew a thing or two, as this statement to a
Warren Commission interviewer shows:
I look at America. It’s all wonderful. But you go to the damn grocery store
and it’s 200 varieties of cereal and basically it’s only oats, corn – how many
things? Just so someone can make an extra million off of that. It’s just so
unnecessary. If that’s progress, if that’s abundance, how stupid is it of us to
want it? Three hundred bags of poison, maybe only two or three good – that kind
of progress…I don’t think we should strive for.
Lee Harvey Oswald’s solitary Marxism was the ideology that allowed an
intelligent young man to compensate for the loss of his father and an
upbringing by one of history’s more blameable mothers. It provided him with
inspiration for grandiose fantasies and daring acts, as well as a feeling of
intellectual importance that compensated for learning difficulties, diagnosed
posthumously as dyslexia. Oswald had become seriously interested in politics at
the age of 15 or 16 after he was handed a leaflet about Julius and Ethel
Rosenberg, who had been executed some two years earlier for spying for the
Soviet Union, on a street corner in the Bronx (the effect this interaction had
on him may have influenced his later decision to hand out Fair Play for Cuba
pamphlets in New Orleans; it seems to have also triggered a Walter Mitty
fantasy life as an espionage hero which lasted the rest of his life). “I was
looking for a key to my environment, and then I discovered socialist
literature,” Oswald wrote in his diary. “I had to dig for my books in the back
of dusty shelves of libraries,” although according to Priscilla McMillan, he
came across more as the naïve angry young man than a perceptive Marxist in their
5-hour Moscow interview despite using “a good deal of Marxist language”. The Oswald that stalks the pages of Marina
and Lee is also a familiar character to readers of criminal profiling books,
a case-study of the violent malcontent male loner. An American outsider who
married a Russian outsider, and who was closer to Russian-speaking outsiders
than to anyone else outside his family back in the USA, Lee Oswald read Orwell
and Dostoyevsky, listened to Rimsky-Korsakoff, Chaliapin, Rachmaninov, and
Tchaikovsky, and in his more constructive activities was inspired by Marxist
newspapers The Worker and The Militant. He is holding copies of both these papers
in the famous photographs Marina took of him with his guns, one of which, with
a Russian inscription on the back – “hunter of fascists – ha ha ha!” in
Marina’s hand, signed by Oswald, was given to their friend George De
Mohrenschildt, the edgelord of the Dallas Russian émigré scene who parodies an
éminence grise role in their story.
The Worker was the paper of the U.S. Communist Party, The Militant of
the Trotskyist Socialist Workers Party; Oswald corresponded with both journals,
in a futile attempt to establish credibility as a leader of the organized left;
the March 11 1963 copy of The
Militant he is holding contains a letter headed “News and Views from
Dallas”, signed LH, which was the high point of his association with organised
socialism in America. 
Lee Oswald was a person who would lie or withhold the truth whenever possible,
so that he moved in a web of misdirection, but also presumably in a state of
tension lest his lies (which include a long list of needless lies on official
forms) be found out. He starved himself and Marina, as his mother had starved
him, and pinched pennies as she had - what conspiracy asset would have been
left as bereft of financial support as the Oswalds were at times, or as
dependent on the kindness of strangers, who liked Marina but rarely liked
ungrateful and ungracious Lee, and sometimes feared him? He was violent and
controlling towards Marina, and beat her often, but became less violent at home
after his attempted assassination of General Walker altered their relationship;
he was also often cruel to her, as if practicing the heartlessness essential in
a great revolutionary leader, and prevented her learning English for his own
reasons (so that much of the evidence in the case of Lee Harvey Oswald is the
record of conversations held in Russian, remembered by someone who thought in
Russian). Yet Lee, who identified as a Marxist, was never a member of the Communist
party, and recognised that the USSR was less successful than the USA – his core
attitude was a juvenile delinquent’s hostility to any authority he was no
longer capable of idealising, and a contempt for almost all other people, but
as a strongly self-entitled person of progressive views he granted, in theory,
everyone else a share in what he himself felt he deserved. As a social justice
warrior, he was capable of admirable performative gestures, such as sitting in
the black section of a segregated courtroom when arraigned in New Orleans,
without seemingly ever going out of his way to perform any act of kindness for
another human being in need.
There is a Jekyll and
Hyde character to Lee’s politics, in which his violent acts contradict both his
written statements and his progressive activism, resembling an expressionistic
caricature of 20th century Marxism. Eleven years after his murder of
Joseph P. Kennedy’s son, the Symbionese Liberation Army, collectivist Marxists
with better childhoods and higher education than Oswald, embarked on a crime
spree which included kidnapping the granddaughter of William Randolph Hearst.
Their goals, motivations and grievances were, though filtered through the
kaleidoscope of LSD, aligned with Oswald’s. Both Oswald and the SLA were
influenced by what Elizabeth Converse, in The War of All Against All,
called “the irrational Communist belief in ultimate world victory”. At its most
extreme, this belief encouraged the accelerationist heresy - the belief that as
Communism was inevitable, historical upheavals within Capitalist societies
brought it closer, the worse the better. The accelerationist Marxist thinks
like the addict who overdoses because the sooner they reach rock bottom, the
sooner they can begin recovery. Thus the Communists of Weimar Germany were
taught to welcome the rise of Hitler and call the liberal democrats who opposed
him “fascists”, thus Posades welcomed the possibilities of nuclear war and alien invasion, thus the
apocryphal Bernie bro voted for Trump. Sigmund Freud gave us the concept of Thanatos.
the organism’s compulsive drive toward dissolution back into the world; Oswald’s
decisions were often thanatic – his defection to the USSR, which involved
cutting his left wrist and attempting to surrender his US citizenship, his
assault on the Soviet bureaucracy to get both himself and Marina back to
America, the time he shot at Walker, the time he stuck a pistol in his belt and
said he was going to “have a look” at Richard Nixon (defused by Marina), the
similarly defused planning to hijack an airliner to Cuba, the assassination
itself, his refusal to consider that he might become a target afterwards.
On the morning of the 22nd of November 1963, Lee Oswald left $170
for Marina, whom he had, up to that point seldom allowed any cash at all, as
well as the wedding ring he never took off, collected his rifle, and went to
work at the Elm street branch of the Texas Schoolbook Depository. There, from a
window on the East side of the fifth floor, he shot dead U.S. President John F.
Kennedy and wounded John Connally, the Governor of Texas; later that day Lee
Oswald would kill Patrolman J.D. Tippit with the cut-off Smith and Weston .38
pistol he had mail-ordered long before the rifle, but which had arrived on the
same day.
Had Lee Oswald stood trial, his guilt would have been presented as a coherent
narrative, and his motivations widely discussed, as he intended. Instead, he
was shot dead two days later by Jack Ruby in an act almost as impulsive and
last-minute as his own. Ruby’s motives are obscure – even more unstable and
violent than Oswald, he was a heavy consumer of phenmetrazine, the new
amphetamine also popular with The Beatles, was only 5 blocks from the
assassination when it happened, and became paranoid that Jews would be blamed
for the assassination, resulting in a pogrom.
The original complaint filed by the Dallas police department on Lee Oswald,
around midnight on the 22nd of November, said that Lee Oswald did, "in
furtherance of an international communist conspiracy, assassinate President
John F. Kennedy,” but Oswald’s murder, and the lack of evidence against anyone
else he knew, meant that charge would not be tested in a court of law.
The possibility that Oswald's political convictions may have played a
decisive part in his shooting John F. Kennedy was down-played in the early
1960s because President Johnson and other officials did not want the
assassination to become a casus belli with the Soviet Union. And to the public,
this explanation, at a moment when capitalism was riding high, appeared
ludicrous. Besides, for a Marxist, killing this president appeared wildly
inconsistent. Kennedy was a liberal.
- Priscilla MacMillan, JFK and Oswald: The Inconvenient Truth
It may have also have
mattered that no-one wanted to revisit McCarthyism. Sen Joseph McCarthy had
been defeated by censure in 1954 and died in 1957; the House Unamerican
Activities Committee lingered until 1975 but by 1963 was beginning to come
under siege from an emerging counterculture that would become increasingly
Marxist as the 60’s turned to the 1970’s. Overseas, US foreign policy and
covert interventions would ensure the abduction, torture and death of many
thousands of Marxists through the next few decades, yet in the USA the few
leftists who knew Oswald were not persecuted, and the journals of which he said
"you can see what they want you to do by reading between the lines"
were not supressed.
In December of 1963 Dylan, then in the most activist stage of his folk career,
was an attendee at a dinner event in New York hosted by the Emergency Civil
Liberties Committee, which had awarded him its annual Tom Paine Award.
“I’ve got to admit that the man who shot President Kennedy, Lee Oswald, I
don’t know exactly where — what he thought he was doing, but I got to admit
honestly that I too — I saw some of myself in him. I don’t think it would have
gone — I don’t think it could go that far. But I got to stand up and say I saw
things that he felt, in me — not to go that far and shoot.”
The outraged crowd then expressed its hostility to the speaker.
“You can boo but booing’s got nothing to do with it. It’s a — I just a —
I’ve got to tell you, man, its Bill of Rights is free speech and I just want to
admit that I accept this Tom Paine Award in behalf of James Forman of the
Students Non-Violent Coordinating Committee and on behalf of the people who
went to Cuba.”
Fair play for Cuba.
Perhaps the first
conspiracy theory about the assassination, after the statement of the Dallas
PD, was held covertly – the branch of the CIA working on mind control research
must logically have begun looking for evidence of a “Manchurian Candidate”
brainwashing of Oswald by the KGB. The MKULTRA program, initiated in 1953, had
failed to find any reliable form of brainwashing – they had been able to
produce “vegetables” among their guinea pigs but not effective agents or
reliable informants. The program’s budget would be reduced in 1964, but if
there was the possibility that the Soviets or Cubans had succeeded in
brainwashing Oswald then it could be kept alive, and perhaps vindicated. It was
probably in this spirit that MKULTRA researcher Louis Jolyon West interviewed
Jack Ruby in 1964, likely with the use of hypnosis and sodium pentothal. During
the visit Ruby experienced a “psychotic break”, revisiting his delusion of a
Kennedy-assassination inspired pogrom. Jolyon West, who killed the elephant
Tusko with LSD and other drugs in 1962 and studied hippies with MKULTRA in
Haight-Ashbury in late 1967, would later testify at the trial of temporary
Marxist Patty Hearst in support of her defence’s brainwashing theory.
As Jolyon West was infiltrating the hippie subculture in search of the
mind-control McGuffin, David Crosby was ending his career in The Byrds on stage
at the Monterey Pop festival, by introducing the song He Was a Friend of
Mine, a tribute to JFK, with a categorical statement of the most enduring
of the JFK theories –
When President Kennedy
was killed, he was not killed by one man. He was shot from a number of
different directions — by different guns. The story has been suppressed,
witnesses have been killed, and this is your country.
This moment marks the overground advent of progressive conspiracy theory, with
its roots in Eisenhower’s Military-Industrial Complex warning, and its
motivation in opposition to the Vietnam war, and more to the point, in
opposition to the drafting of young American men, who naturally adapted
conspiracy theory as a defence against the mass disposal of their minds and
bodies by the State – analogous to the adoption of conspiracy theory defences
today by those whose autonomy and future plans have been threatened by their
conscription in the war against COVID-19. It was widely rumoured that LBJ,
Kennedy’s Vice President and successor, under whom America had become most
stickily entangled in Vietnam, had ordered the hit, but Richard Nixon and Henry
Kissinger were about to show the USA, and the world, how real political
conspiracies are constructed.
It was in this environment of renewed conspiracy ferment that Kerry Thornley, who had known Oswald in
the US Marines and written a book inspired by his personality, The Idle
Warriors, before the assassination, initiated Operation Mindfuck, with the
help of Greg Hill, Robert Shea and Robert Anton Wilson. Operation Mindfuck
introduced the Illuminati, through letters and ads in Playboy and other “hip”
publications, to the US counterculture, with the intent of parodying the
counterculture conspiracy industry and serving up an anti-stupidity vaccine with
a side-order of chaos and fun. But Thornley and his accomplices underestimated
the forces they were toying with, especially the human tendency to believe in
malign machinations that can explain one’s own apparent impotence, dehumanise
those in control, and undermine the achievements of those who have succeeded in
one’s place, the same need to feel one’s weakness justified as cursed and, if
one can do nothing worse, curse back that fed the belief in witchcraft in the
Middle Ages and that in modern Africa.
While the Jews and Freemasons theories of the Right did not go away, they were
quaintly old-fashioned and smelled strongly of old library books by the 1970’s,
unable to keep up with the actual conspiracies and political and cultural developments
of the Nixon-Kissinger period. The Satanic Abuse panic of the 80’s-90’s was the
most successful attempt to upgrade them – arguably this succeeded, to the
extent that it disrupted civil society, because it aligned with Marxist
Feminist agitation against sexual exploitation; sexual Satanism was a predictable
manifestation of the Patriarchy, and vice versa. Meanwhile, Hunter S Thompson had
created new myths of the operation Mindfuck type, giving adrenochrome its
backstory and planting a rumour about senator Eugene Muskie, the
less-progressive Democratic candidate for the 1972 Presidential race, being
high on ibogaine, which destroyed his candidacy. Kenny Thornley, instead of
mocking the operation Mindfuck theories – which he, glimpsing the truth about
Oswald, had started - began acting as if he believed in one or the other or all
of them. And a young Oliver Stone, after serving in Vietnam and disapproving of
the whole thing, began thinking about the assassination of JFK, who was
believed posthumously to have been opposed to the War in some way.
Stone’s 1991 film JFK marks the moment when conspiracy theory passed
over from the counterculture and far-right into the mainstream; it featured an
impressive cast of A-list actors who presumably approved of its message of suspicion.
JFK was followed by The X-Files TV series in 1993, with its
telling slogan “I want to believe”. The X-Files was ironic enough,
unlike Stone’s breathless film, but this didn’t inhibit the mass distribution
and discussion of its ideas. Both JFK and The X-Files posit an
all-powerful, yet successfully concealed Deep State for which the elected US
government is window-dressing and easily removed if it objects. All around the
world, this gave an easy explanation to those who resented US cultural hegemony
and military power but were not the type to organise against them. It helped
that it was a seemingly playful explanation, one that didn’t insist on being
taken seriously enough to really test, even as it established itself in the
zeitgeist.
Prior to 2001 the Deep State conspiracy theories had to co-exist with the rest
of the Fortean world represented in The X-Files. UFOs, Bigfoot, spontaneous
combustion, the Bermuda triangle, vampires - by the end of the 20th
century, several different species of UFO-riding aliens were abducting and
probing people all around the world. But after 9/11, Islamist terrorists became
the aliens and monsters we watched out for and it was the US state that began
abducting and probing people everywhere; reports of UFO sightings and alien abductions
went into serious decline. As the plainly venal team of Bush, Cheney and
Rumsfeld openly conspired to roll back freedoms and push the world into another
unwinnable war, a spontaneous conspiracy of sorts arose to undermine their casus
belli by suggesting that the terror attacks had been an inside job. This
also meant not admitting that a Saudi Arabian NGO could get the better of the
mighty USA, so it had cross-party appeal, but the list of progressive
celebrities who endorsed or indulged 9/11 conspiracy theories is almost as
impressive as the cast of JFK, and included Ed Asner, Spike Lee, Woody
Harrelson, Rosie O’Donnell, Marion Cottillard and Graham Nash. Spreading a
rumour like “Bush did 9/11” is a way of cursing the powerful, a displacement
activity born of impotence and frustration, like spreading a rumour that your
local feudal tyrant worships Bahomet because you are powerless to stop him
taking what he wants from you. And 20 years later, Q-Anon is simply the
aggregate of all the progressive counterculture conspiracy theories, including
Kerry Thornley and Hunter S Thompson’s inventions, with a modified Satanic
abuse element, and with the older Jews, Freemasons and Communists theories always
sneaking back in.
It all began with Oswald and the trauma he induced in the USA on November
22 1963. As NBC News anchor
David Brinkley said, as he signed off that night, Kennedy’s death was “just too
much, too ugly and too fast.” In 2007 Priscilla MacMillan summed up the
aftermath of the assassination in a short article for World Policy Journal
titled JFK and Oswald: The Inconvenient Truth.
Oswald's act of violence indisputably
ushered in an era of unease and suspicion in American life that was not there
prior to the Kennedy assassination. Oswald was not responsible for all of the
damage that has befallen American society since 1963, much as he would have
wished to be. Some of that damage is the result of events related only
tangentially to the assassination of President Kennedy. But some of the injury
can, with justice, be attributed to conspiracy theorists who have gone to
superhuman lengths to avoid facing the truth. They have constructed
wildly-implausible scenarios, far-out, fictitious "conspirators," and
have scandalously maligned the motives of Kennedy's successor, rather than take
a hard look at the man who actually did it. They have, ironically, done more to
poison American political life than Lee Oswald - with the most terrible of
intentions - was able to do.
Kerry Thornley thought that a little light Illuminati hoaxing would make
people immune to conspiracy theories, but conspiracy theories, as The
X-Files and its spin-off The Lone Gunmen have proved, are immune to
spoofing; Q-Anon is a spoof of spoofs, and it has outshone them all.
If the world is ready to give Marina Oswald’s story and Priscilla MacMillan’s
research and analysis the same attention it once gave to Jim Garrison’s speculations,
narrative will replace montage in the JFK storytelling tradition. In the near
future there will be a film, or better yet a TV series, of Marina and Lee,
based on the True Crime book of that name which its viewers will queue to read.
In our contemporary state of disinformation
hypersensitivity, it should get a more reasoned reception from the comments
section than the PBS Frontline documentary series Who
Was Lee Harvey Oswald did when it rescreened in 2013. We will come to
understand Lee Oswald and the ideological world he inhabited, which is closer
to our own than used to be the case, because the expression of low-constraint
or heretical or otherwise deviationist versions of Marxist ideas is now
commonplace, because glasnost revisionism, 90 Day Fiancé, RT, and Red
Scare have made Marina’s voice more relatable, and because we’re now well-used
to seeing violent malcontent male loners acting out the terrorist fantasies which
they developed through ideological study and travel.
Imagine a counterfactual America, an alternative history wherein it has always
been a well-known and accepted fact that Lee Harvey Oswald, a lone-wolf
Marxist, assassinated the 35th President of the United States.
George Henderson, Auckland, Sept 2021
Addendum:
The killing of Oswald by Jack Ruby was the real singularity that tipped America down the path to Q-Anon, as it removed Oswald from his own story. I've called Ruby's motives "obscure" above, but obscure as they are they are not beyond all speculation. Here's what I think.
Roy Cohn, as a patriotic American Jew trying to succeed in the system, persecuted Jewish American communists because he thought they gave a bad impression of American Jews - he more-or-less framed Ethel Rosenberg and brought about her execution. This was the injustice that led to the radicalization of the young Oswald.
The Dallas newspapers had been carrying adverts against JFK that in the opinion of many at the time amounted to hate speech, and some of these were signed by Jewish Republicans (the Republican party still being the old party of tolerance for many, I suppose). Ruby was concerned about this even before the shooting, and when he heard about it panicked that the Jews would be blamed for killing JFK (as, I suppose, they had been for killing Christ) and was compelled to kill Oswald to clear their name, as a kind of sacrificial lamb for his people.
Because this involved magical thinking, and because he may have found it embarrassing in his lucid moments, Ruby gave the more innocent explanation that he had killed Oswald to spare Jackie Kennedy the pain of a trial.
Roy Cohn would go on to become the mentor of Donald Trump, and Donald Trump would go on to become the patron and beneficiary of Q-Anon.
Friday, 30 July 2021
Virta Health vs Seidelmann - of ketones and COVID-19
There were 568 COVID-19 cases and 2316 controls. Among the 568 cases, 138 individuals had moderate-to-severe COVID-19 severity whereas 430 individuals had very mild to mild COVID-19 severity. After adjusting for important confounders, participants who reported following ‘plant-based diets’ and ‘plant-based diets or pescatarian diets’ had 73% (OR 0.27, 95% CI 0.10 to 0.81) and 59% (OR 0.41, 95% CI 0.17 to 0.99) lower odds of moderate-to-severe COVID-19 severity, respectively, compared with participants who did not follow these diets. Compared with participants who reported following ‘plant-based diets’, those who reported following ‘low carbohydrate, high protein diets’ had greater odds of moderate-to-severe COVID-19 (OR 3.86, 95% CI 1.13 to 13.24). No association was observed between self-reported diets and COVID-19 infection or duration.
The methods state
Lastly, we combined ‘low carbohydrate’ diets and ‘high protein’ diets into another category (‘low carbohydrate, high protein diet’, n=483) to evaluate whether these dietary patterns are associated with COVID-19 severity.
There was a keto option, so why didn't they add keto + low carb?
Methods state
Before analyses, we selected dietary patterns with sufficient ‘yes’ responses (‘yes’ response of at least 100 individuals). To increase precision, we analysed three dietary patterns after combining dietary patterns that are similar in terms of dietary intake.
Perhaps keto had less that 100 responses? But there was no registered protocol, those decisions were post-hoc - even if keto had fewer than 100 responses, adding it would have still increased numerical power, which was presumably the point of combining categories as they did. And there's nowhere it says how many responses, and we also have no way of knowing how similar low carb and high protein really were (everything was pretty similar really, these were for most respondents just the virtue-signaling labels they gave to their eating habits).
Anyway, there was no association once people with a negative or no PCR test were excluded.
That's not in the abstract.
But, you know, people are using the keto and LCHF diets to treat diabetes and reduce COVID19 mortality associated with type 2 diabetes, MetSyn, or obesity, so this is a nasty thing to say if it's not true. It's a bit like trying to get people to stop taking vaccines based on your bias and some shit you didn't understand.
Fortunately Vitra Health have ridden to the rescue with a survey of their own T2D population on a ketogenic diet. We know these people are actually following the diet, or adhering closely to it.
The abstract (presented at an ADA conference) is
COVID-19 Severity in a Geographically Diverse, U.S.-based, Ambulatory Population with Type 2 Diabetes on a Medically Supervised Ketogenic Diet
Let's compare with the Seidelmann paper - 1) we know the diet is real. 2) COVID-19 is self-reported (some will have tests some not, as in Seidelmann) but - we do have people being hospitalised, unlike Seidelmann, and we even have one death, so Virta are able to capture events that people weren't able to report directly, because their model includes liaison with primary providers likely to report deaths to them. 3) the event rates are low for a population with type 2 diabetes, as shown by the comparison with this population. The populations, though much the same age, aren't identical, but the biggest difference seems to long term inclusion in the Virta Health population (note the "baseline" HbA1c data in Virta - before treatment with the ketogenic diet - is similar to the overall HbAic data in the comparator vs standard practice, but many of the Virta Health population have put their T2D in remission. At this stage, we have to say that the EFFECTS of the keto program are protective - weightloss and euglycaemia, etc. We don't have evidence that keto per se is protective apart from those factors. But that may well be hidden in the data, once the whole set is fully written up. But once again, it looks like Harvard is a bad actor, an ill informant in the nutrition-and-health space, interfering with effective treatments to preserve its own ill-gotten (by a process of bloviation if not graft) dietary hegemony.
Wednesday, 7 July 2021
The Carb-Fat Food Quality Gradient - a real metabolic advantage
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By now, we've all seen them - studies that purport to show equivalent effects of LCHF and HCLF diets once diet quality is addressed and people are Eating Whole Unprocessed Foods.
The latter is a good thing, the default to go for in terms of population health; macronutrient tweaking is next-level.
But here's a question - why were almost all the original studies that validated the efficacy of LCHF diets to a skeptical medical world comparisons of ad lib low carb vs energy-restricted low fat?
To make a really low carb high fat diet (unless you want to pretend a high-protein diet is that) you're going to be using some isolated fats (cream) or refined ones (coconut oil, olive oil). There may not be sugar in your chocolate bar, but there will be cocoa butter.
This only works if in some way those isolated fats are NOT equivalent to sugar and flour.
What is the evidence for a difference?
One of the more lasting concepts in carb nutrition is the glycemic index, the average speed at which a food appears as glucose in the system. It's not perfect because sugar is only half glucose so is lower GI, but you get the idea.
High GI is worse for you.
The PURE study is good for producing null results, which makes whatever it does throw up seem a bit more reliable than most nutritional epidemiology.[1]
"In the study population, 8780 deaths and 8252 major cardiovascular events occurred during the follow-up period. After performing extensive adjustments comparing the lowest and highest glycemic-index quintiles, we found that a diet with a high glycemic index was associated with an increased risk of a major cardiovascular event or death, both among participants with preexisting cardiovascular disease (hazard ratio, 1.51; 95% confidence interval [CI], 1.25 to 1.82) and among those without such disease (hazard ratio, 1.21; 95% CI, 1.11 to 1.34). Among the components of the primary outcome, a high glycemic index was also associated with an increased risk of death from cardiovascular causes. The results with respect to glycemic load were similar to the findings regarding the glycemic index among the participants with cardiovascular disease at baseline, but the association was not significant among those without preexisting cardiovascular disease."
As I've said before, everything in plants that is supposed to be good for you but isn't actually a real nutrient is probably lowering GI in some way. It's the glucose (glycemic load above) but the way it arrives in your bloodstream (GI) is more pointed.
Is there equivalency for fats? Do fats that are rapidly absorbed correlate with disease?
That would be the medium chain fatty acids, MCFA.
"In comparison to triglycerides containing LCFAs, those containing MCFAs are more rapidly hydrolyzed in the intestinal tract and do not become incorporated into chylomicrons. SCFAs and MCFAs are transported by portal bloodstream to the liver, where they are readily metabolized."[2]
And perhaps also the unsaturated fatty acids, UFA.
"Although pancreatic lipase hydrolyzes fat only in the 1 and 3 positions of the molecule, it is nevertheless possible for fatty acids in the 2 position of the triacylglycerol to be hydrolyzed. This apparent violation of the specificity of pancreatic lipase occurs because of the relative instability of both the 2-monoacylglycerol and the 1,2-diacylglycerol (Crossley et al., 1959). These molecules rearrange by migration of the fatty acid in the 2 position to the 1 or 3 position, which is readily hydrolyzed by lipase (Figure 18–3). This rearrangement is more rapid when the fatty acid is either a short-chain one or an unsaturated one, and a portion of the 2-position fatty acids may be absorbed as fatty acids rather than as monoacylglycerols (Benzonana et al., 1964)."[3]
We'll call this the fat index, FI.
Are fatty acids with a high FI worse than low-FI fats?
No.
In epidemiological studies of individual fatty acids and their associations with disease risk, the MCFAs, which are SFAs, are always more benign than the longer-chain SFAs (see table 2).[4]
"Two recent studies from the Netherlands reported largely diverging findings. In the European Prospective Investigation into Cancer and Nutrition study, intakes of 4:0-10:0 and 12:0 were inversely associated with ischemic heart disease risk, but no associations were found for 14:0, 16:0, and 18:0. However, in the Rotterdam study, only 16:0 intake was associated with higher risk of coronary heart disease." [see also table 2]
In an overfeeding experiment, the benefits of MCFA were obvious.[5]
"In conclusion, substitution of a small amount of dietary LCFAs with MCFAs rescues insulin action in conditions of lipid-induced energy excess."
This is because high-FI fatty acids are metabolized more rapidly, and, in the case of MCFAs, oxidized with less metabolic and hormonal effort than LCFA.[2,6]
In conclusion - if you eat carbs in bulk you will need to pay some attention to the speed at which your body absorbs them; this rules out eating purified carbohydrates.
If you eat fats in bulk, you need pay little attention to the speed your body absorbs them; you may want more fast-absorbing fatty acids in your food, but this does not rule out eating purified fats.
[1] Jenkins DJA, Dehghan M, Mente A, Bangdiwala SI, Rangarajan S, Srichaikul K, Mohan V, Avezum A, Díaz R, Rosengren A, Lanas F, Lopez-Jaramillo P, Li W, Oguz A, Khatib R, Poirier P, Mohammadifard N, Pepe A, Alhabib KF, Chifamba J, Yusufali AH, Iqbal R, Yeates K, Yusoff K, Ismail N, Teo K, Swaminathan S, Liu X, Zatońska K, Yusuf R, Yusuf S; PURE Study Investigators. Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality. N Engl J Med. 2021 Apr 8;384(14):1312-1322. doi: 10.1056/NEJMoa2007123. Epub 2021 Feb 24. PMID: 33626252.
https://www.nejm.org/doi/full/10.1056/NEJMoa2007123
[2] Schönfeld P, Wojtczak L. Short- and medium-chain fatty acids in energy metabolism: the cellular perspective. J Lipid Res. 2016;57(6):943-954. doi:10.1194/jlr.R067629
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878196/
[3] Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations. Washington (DC): National Academies Press (US); 1994. 18, Structured Lipids: An Overview and Comments on Performance Enhancement Potential. Available from: https://www.ncbi.nlm.nih.gov/books/NBK209064/
[4] Zong G, Li Y, Wanders A J, Alssema M, Zock P L, Willett W C et al. Intake of individual saturated fatty acids and risk of coronary heart disease in US men and women: two prospective longitudinal cohort studies BMJ 2016; 355 :i5796 doi:10.1136/bmj.i5796
https://www.bmj.com/content/355/bmj.i5796
[5] Anne-Marie Lundsgaard, Andreas M. Fritzen, Kim A. Sjøberg, Maximilian Kleinert, Erik A. Richter, Bente Kiens. Small Amounts of Dietary Medium-Chain Fatty Acids Protect Against Insulin Resistance During Caloric Excess in Humans.
Diabetes Jan 2021, 70 (1) 91-98; DOI: 10.2337/db20-0582
https://diabetes.diabetesjournals.org/content/70/1/91
[6] James P DeLany, Marlene M Windhauser, Catherine M Champagne, George A Bray, Differential oxidation of individual dietary fatty acids in humans, The American Journal of Clinical Nutrition, Volume 72, Issue 4, October 2000, Pages 905–911, https://doi.org/10.1093/ajcn/72.4.905
Sunday, 27 June 2021
Probiotic extracts for PTSD - proof of concept for the gut-brain axis?
It happened like this - having noticed that probiotics were helping with my HCV symptoms, I was theorising about the reasons for this in a Hep C forum with nurse Silvia H, who supplied a lot of my early background on immunity; this attracted the notice of Elizabeth McKenna, who was working with Beth Jones, the senior author of the present paper. Dr Jones had invented a process for producing a cell wall lysate from bacteria that, or so it was claimed, preserved the probiotic immune function to a far greater extent than other lysates and heat-killed probiotic products then available.
I knew a bit about these products because a friend with HCV swore by a product called Del Immune V, which had corrected what seemed to be autoimmune symptoms. I tried this product but to be honest was already so saturated with effective herbs and other supps that I couldn't honestly say what it did, though it did appear to be something. But by looking on the interwebs, as they then were, I could deduce a bit about such things.
My theory was, still is, that commensal bacteria - as well as herbs like astragalus and some mushroom sp. produce polysaccharides and other PAMP signaling molecules that mimic LPS in a benign way. An agonist-antagonist relationship with PAMP receptors could explain this modified version of the effect (this is why it can be useful having a druggie on the board, pharma execs). This summary minimizes the amount of reading I did on complement and alternative complement pathways, Tregs and Th17, retinoid metabolism and immune cell differentiation, dendrite cell translocation of LPS, and other things that mercifully I only faintly remember now. Anyway, it looked as if the toll-like receptors, a major PAMP recognition pathway, were important.
Elizabeth McKenna, by now the CEO of Labyrinth holdings overseeing the patent process for Dr Jones, had the realization that TLR activity was assayable - the tests were done and, as in the current paper, there was significant activity at several PAMP receptors.
Soon after I received some test samples of the product, now called ReseT. From Reset T cells - a good concept but as it turned out a very poor name when it came to finding the product in search engines!
Anyway, at the time I still had HCV, and that was one possible use for ReseT, so I thought I should try it. Even though at the time my symptoms were under control and I had no idea if I would notice, because that's how I roll, someone has to try things and I was already implicated, as it were.
We know know that the dose I took was about twice what's optimal. It's a sublingual lactose-based pill, or was, and the effect was rapid. The pattern on the carpet in front of me softened, life softened, and I felt something very similar to the effect of valium or some other GABA agonist. Well that's quite impressive I thought, but it left me fully functional and I was on my way to a Neil Young concert.
While on the way I smoked a couple of strong joints.
Then there I was, trapped indoors with thousands of strangers in a swirling mob.
This sort of thing is of course a recipe for social anxiety, and it's normal to negotiate this effect, which can get quite harsh, if you're a stoner who wants to be really stoned for, you know, NEIL.
But this time things were completely different - I was immune to anxiety. And I remained immune to anxiety from this cause for a long time after I stopped taking ReseT, which I didn't take regularly for long, and it's never really been all that strong ever again.
Now, the experiential effects I've described haven't been described by anyone else - that is, no-one else who's benefitted from ReseT since seems to have observed the point at which it happened in the way I did. That's Okay, I'm used to being highly observant of such things, even though it gets me laughed at sometimes. I only noticed the strong GABA effects on the first two or three occasions I took ReseT, fading as I became less prone to anxiety.
Anyway I drifted away from the probiotic problem as other work came along, and though Elizabeth McKenna kept in touch I did think the proposed mechanism, that the effect can be explained by the manipulation of oxidative stress, was putting too much onus on the immune system. and too much responsibility on bacteria.
But obviously I didn't have all the facts that the people on the ground did, and as it happens there's nothing better than a highly simplistic hypothesis - IF the evidence supports it.
If the evidence supports a simple explanation, there is no immediate requirement for terms like complex and multifactorial. To paraphrase William of Occam.
In the first of two papers, A pilot study: Innate immune modulation reduces F2-Isoprostanes and improves psychological health in a chronically stressed cohort
https://onlinelibrary.wiley.com/doi/10.1002/hsr2.289
Seven male participants (combat veterans aged between 28 and 47 years) with PTSD completed the 70-day study.
The study design was a single-arm treatment study, wherein the effects of treatment were assessed and compared to the baseline pretreatment values (Day 1). Once the baseline samples were collected, the study participants were requested to take two 12 mg tablets, sublingually, twice daily (48 mg daily dose) for the duration of the study, and maintain their normal daily routine. Treatment sample collection and the measurements were performed on Days 15 and 70.
The graphs demonstrate after 14 days of treatment, most of the participants experienced improved psychological health that were consistent with reduced urinary levels of F2-IsoP (Figure 1A). In case of depression profiles, there was significant improvement observed by Day 15 (Figure 1D). However, with further treatment, the participants continued to exhibit improvement, with significant improvement in the metrics of life satisfaction (Figure 1B) and daytime sleepiness (Figure 1C) by Day 70. The correlation coefficients between the F2-IsoP and mental health parameter values were −0.99, 0.99, 0.95, and 0.96 for life satisfaction, sleepiness, depression, and anxiety, respectively.
To be sure, the study wasn't controlled. But a placebo effect shouldn't lower F2-IsoP that much, and I think it very unlikely that placebo effects can be maintained this consistently for 55 days, especially given the very minimal interaction between participants and clinicians during the study. But note that the antianxiety effect I noticed is probably only being experienced by one or two participants.
Anyway, placebos shouldn't affect drosophila, and there's also a fruit fly study that corroborates that ReseT is bioactive (via NF-κβ).
Treatment with Bacterial Biologics Promotes Healthy Aging and Traumatic Brain Injury Responses in Adult Drosophila, Modeling the Gut–Brain Axis and Inflammation Responses
https://www.mdpi.com/2073-4409/10/4/900
Here, we examine the response of adult Drosophila given an inactive bacteriologic (IAB; proprietary lysate preparation of Lactobacillus bulgaricus, ReseT®) and a probiotic (Lactobacillus rhamnosus, LGG). In vitro, the IAB activates a subset of conserved Toll-like receptor (TLR) and nucleotide-binding, oligomerization domain-containing protein (NOD) receptors in human cells, and oral administration slowed the age-related decline of adult Drosophila locomotor behaviors. On average, IAB-treated flies lived significantly longer (+23%) and had lower neural aggregate profiles. Different IAB dosages also improved locomotor function and longevity profiles after traumatic brain injury (TBI) exposure. Mechanistically, short-term IAB and LGG treatment altered baseline nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κβ) signaling profiles in neural and abdominal tissues. Overall, at select dosages, IAB and LGG exposure has a positive impact on Drosophila longevity, neural aging, and mild traumatic brain injury (TBI)-related responses, with IAB showing greater benefit. This includes severe TBI (sTBI) responses, where IAB treatment was protective and LGG increased acute mortality profiles.
Well. Interestingly there may be a "too much" point here with both interventions where they are no longer great, with a lower tolerance for the live probiotic. These are not placebos.
Anyway L. Bulgaricus was the probiotic that Élie Metchnikoff predicted would extend life in 1907.
Just sayin'.
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| Tolstoy and Metchnikoff, |
Disclaimer - my work for Labyrinth in its early days was pro bono, and I've never been paid by anyone involved. I did receive two textbooks.






